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Investigación
Evaluación de riesgo
Líneas de investigación
Contenidos con Investigacion .
Evaluación de riesgo
La unidad colabora y proporciona asesoramiento científico-técnico a diversas organizaciones internacionales, como la European Partnership for Alternative Approaches to Animal Testing (EPAA), la Organización de las Naciones Unidas para la Alimentación y la Agricultura (FAO) y la Unión Internacional de Química Pura y Aplicada (IUPAC). Además de realizar evaluaciones de riesgo regulatorias de sustancias químicas, estamos involucrados en proyectos de investigación que desarrollan nuevas metodologías de evaluación de riesgo. Las líneas de investigación incluyen el desarrollo, utilización e implementación de:
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- “Integrated Approaches to Testing and Assessment (IATAs)” para evaluar de manera integral los riesgos de las sustancias químicas, combinando diferentes fuentes de datos y evidencia, como datos in vitro, in silico y estudios en animales.
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- “Adverse Outcome Pathways (AOPs)” y redes AOPs para comprender mejor los mecanismos moleculares y biológicos que conducen a los efectos adversos en la salud humana y el medio ambiente como resultado de la exposición a sustancias químicas.
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- Métodos de evaluación de riesgos probabilísticos que tienen en cuenta la variabilidad inherente en los datos y las incertidumbres asociadas con los procesos de evaluación. La interpretación de resultados y series de datos existentes nos permite obtener un valor añadido en términos de efectos sobre la salud, humana o ambiental, así como la integración de diferentes fuentes de información.
Publicaciones destacadas
A Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Using Human Biomonitoring Data.
1. Tarazona, J. V., Cattaneo, I., Niemann, L., Pedraza-Diaz, S., González-Caballero, M. C., de Alba-Gonzalez, M., Cañas, A., Dominguez-Morueco, N., Esteban-López, M., Castaño, A., Borges, T., Katsonouri, A., Makris, K. C., Ottenbros, I., Mol, H., De Decker, A., Morrens, B., Berman, T., Barnett-Itzhaki, Z., … Santonen, T. (2022). A Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Using Human Biomonitoring Data. Toxics 2022, Vol. 10, Page 451, 10(8), 451.
DOIApplicability of Food Monitoring Data for Assessing Relative Exposure Contributions of Pyrethroids in Retrospective Human Biomonitoring Risk Estimations.
2. de Alba-Gonzalez, M., González-Caballero, M. C., & Tarazona, J. V. (2024). Applicability of Food Monitoring Data for Assessing Relative Exposure Contributions of Pyrethroids in Retrospective Human Biomonitoring Risk Estimations. Toxics, 12(1), 24.
DOIHow to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU.
3. Santonen, T., Mahiout, S., Alvito, P., Apel, P., Bessems, J., Bil, W., Borges, T., Bose-O’Reilly, S., Buekers, J., Cañas Portilla, A. I., Calvo, A. C., de Alba González, M., Domínguez-Morueco, N., López, M. E., Falnoga, I., Gerofke, A., Caballero, M. del C. G., Horvat, M., Huuskonen, P., … Schoeters, G. (2023). How to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU. International Journal of Hygiene and Environmental Health, 249, 114139.
DOIImproving the Risk Assessment of Pesticides through the Integration of Human Biomonitoring and Food Monitoring Data: A Case Study for Chlorpyrifos.
4. Tarazona, J. V., González-Caballero, M. D. C., de Alba-Gonzalez, M., Pedraza-Diaz, S., Cañas, A., Dominguez-Morueco, N., Esteban-López, M., Cattaneo, I., Katsonouri, A., Makris, K. C., Halldorsson, T. I., Olafsdottir, K., Zock, J. P., Dias, J., De Decker, A., Morrens, B., Berman, T., Barnett-Itzhaki, Z., Lindh, C., … Castaño, A. (2022). Improving the Risk Assessment of Pesticides through the Integration of Human Biomonitoring and Food Monitoring Data: A Case Study for Chlorpyrifos. Toxics, 10(6), 313.
DOIMethylmercury Risk Assessment Based on European Human Biomonitoring Data.
5. Domínguez-Morueco, N., Pedraza-Díaz, S., González-Caballero, M. del C., Esteban-López, M., de Alba-González, M., Katsonouri, A., Santonen, T., Cañas-Portilla, A., & Castaño, A. (2022). Methylmercury Risk Assessment Based on European Human Biomonitoring Data. Toxics, 10(8), 427.
DOIPollution, indoor air.
6. González-Caballero, M. del Carmen, de Alba-Gonzalez, M., & Tarazona, J. V. (2024). Pollution, indoor air. Encyclopedia of Toxicology, Fourth Edition: Volume 1-9, 7, 787–799.
DOIEvaluating urban indoor and outdoor PM10-bound organochlorine pesticides. Air quality status and health impact.
7. Galán-Madruga, D., Cárdenas-Escudero, J., Broomandi, P., Cáceres, J. O., & González, M. D. C. (2023). Evaluating urban indoor and outdoor PM10-bound organochlorine pesticides. Air quality status and health impact. Building and Environment, 228, 109818.
DOIInternalization and toxicity of polystyrene nanoplastics on inmortalized human neural stem cells.
8. González-Caballero, M. C., de Alba González, M., Torres-Ruiz, M., Iglesias-Hernández, P., Zapata, V., Terrón, M. C., Sachse, M., Morales, M., Martin-Folgar, R., Liste, I., & Cañas-Portilla, A. I. (2024). Internalization and toxicity of polystyrene nanoplastics on inmortalized human neural stem cells. Chemosphere, 355, 141815.
DOINeurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo.
9. Torres-Ruiz, M., de Alba González, M., Morales, M., Martin-Folgar, R., González, M. C., Cañas-Portilla, A. I., & De la Vieja, A. (2023). Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo. Science of The Total Environment, 874, 162406.
DOIHuman neural stem cells in developmental neurotoxicology: Current scenario and future prospects.
10. Rosca, A., Coronel, R., López-Alonso, V., Liste, I., & González-Caballero, M. C. (2023). Human neural stem cells in developmental neurotoxicology: Current scenario and future prospects. Advances in Neurotoxicology, 9, 197–237.
DOIEffects of 700 and 3500 MHz 5G radiofrequency exposure on developing zebrafish embryos.
Torres-Ruiz, M; Oscar J. Suárez; Victoria López; Pablo Marina; Aránzazu Sanchis; Isabel Liste; Mercedes de Alba; Victoria Ramos. 2024. Effects of 700 and 3500 MHz 5G radiofrequency exposure on developing zebrafish embryos. Science of the Total Environment. 169475.
DOIEffects of nanomolar methylmercury on developing human neural stem cells and zebrafish Embryo
Torres-Ruiz, M; De Alba, M; Coronel, R; Liste, I; Cañas, AI; Gonzalez, M. 2024. Effects of nanomolar methylmercury on developing human neural stem cells and zebrafish Embryo. Food Chem Toxicol. 188:114684.
DOINew approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project.
Tal T, Myhre O, Fritsche E, ….., Torres-Ruiz M, and Bartmann K (2024) New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project. Front. Toxicol. 6:1359507.
DOIInternalization and toxicity of polystyrene nanoplastics on immortalized human neural stem cells
Mª. Carmen González-Caballero; Mercedes de Alba González; Mónica Torres-Ruiz; Ana I. Cañas-Portilla; Patricia Iglesias-Hernandez. Internalization and toxicity of polystyrene nanoplastics on immortalized human neural stem cells. Chemosphere 29:355:141815 2024.
DOINeurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo.
Mónica Torres-Ruiz, Mercedes de Alba González, Mónica Morales, Raquel Martin-Folgar, Mª Carmen González, Ana I. Cañas-Portilla*, and Antonio De la Vieja* 2023 Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo. Science of the Total Environment, 2023 May 20;874:162406.
DOIMolecular effects of polystyrene nanoplastics on human neural stem cells
Raquel Martin-Folgar, Mª Carmen González-Caballero, Mónica Torres-Ruíz, Ana I. Cañas-Portilla, Mercedes de Alba-González, Isabel Liste, Mónica Morales. Molecular effects of polystyrene nanoplastics on human neural stem cells PLOS ONE, enero 2024.
DOIDNA damage and molecular level effects induced by polystyrene (PS) nanoplastics (NPs) after Chironomus riparius (Diptera) larvae
Raquel Martin-Folgar, Celia Sabroso, Ana I. Cañas-Portilla, Mónica Torres-Ruíz, Mª Carmen González-Caballero, Helena Dorado, Ignacio Velasco, Mónica Morales. DNA damage and molecular level effects induced by polystyrene (PS) nanoplastics (NPs) after Chironomus riparius (Diptera) larvae. Chemosphere 346 (2024) 140552
DOINew approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project. Frontiers in Toxicology
Louise Ramhøj, Marta Axelstad, Yoni Baert, Ana I. Cañas-Portilla, Frédéric Chalmel, Lars Dahmen, Antonio De La Vieja, Bertrand Evrard, Ann-Cathrin Haigis, Timo Hamers, Kim Heikamp, Henrik Holbech, Patricia Iglesias-Hernandez, Dries Knapen, Lorna Marchandise, Jane E. Morthorst, Nikolai Georgiev Nikolov, Ana C. V. E. Nissen, Michael Oelgeschlaeger, Kostja Renko, Vera Rogiers, Gerrit Schüürmann, Evelyn Stincken, Mette H. Stub, Monica Torres-Ruiz, Majorie Van Duursen, Tamara Vanhaeck, Lucia Vergauwen, Eva Bay Wedebye, Terje Svingen. New approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project. Frontiers in Toxicology. 2023
DOIMolecular effects of polystyrene nanoplastics toxicity in zebrafish embryos (Danio rerio)
Raquel Martin-Folgar, Mónica Torres-Ruiz, Mercedes de Alba, Ana I. Cañas-Portilla, Mª Carmen González, Mónica Morales. Molecular effects of polystyrene nanoplastics toxicity in zebrafish embryos (Danio rerio) Chemosphere, 2023 Jan;312(Pt 1):137077.
DOIToxicity of nanoplastics for zebrafish embryos, what we know and where to go next.
Torres-Ruiz,M.; De la Vieja,A.; De Alba Gonzalez,M.; Esteban Lopez,M.; Castaño,A.; Cañas Portilla, A.I.; 2021. Toxicity of nanoplastics for zebrafish embryos, what we know and where to go next. Science of the Total Environment 797: 149125.
DOIHuman urinary arsenic species, associated exposure determinants and potential health risks assessed in the HBM4EU Aligned Studies
Buekers J, Baken K, Govarts E, Rodriguez Martin L, Vogel N, Kolossa-Gehring M, Šlejkovec Z, Falnoga I, Horvat M, Lignell S, Lindroos AK, Rambaud L, Riou M, Pedraza-Diaz S, Esteban-Lopez M, Castaño A, Den Hond E, Baeyens W, Santonen T, Schoeters G. Human urinary arsenic species, associated exposure determinants and potential health risks assessed in the HBM4EU Aligned Studies. Int J Hyg Environ Health. 248: 114115. 2023.
DOILiterature review and evaluation of biomarkers, matrices and analytical methods for chemicals selected in the research program Human Biomonitoring for the European Union (HBM4EU)
Sabbioni G, Castaño A, Esteban López M, Göen T, Mol H, Riou M, Tagne-Fotso R. Literature review and evaluation of biomarkers, matrices and analytical methods for chemicals selected in the research program Human Biomonitoring for the European Union (HBM4EU). Environ Int. 169: 107458. 2022.
DOIHarmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014-2021).
Govarts E, Gilles L, Rodriguez-Martin L, Santonene T, Apel P, Alvito P, Anastasi E, et al. Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014-2021). Int J Hyg Environ Health. 249.114119. 2023.
DOIA step towards harmonising human biomonitoring study setup on European level: Materials provided and lessons learnt in HBM4EU.
Pack LK, Gilles L, Cops J, Tolonen H, van Kamp I, Esteban-Lopez M, Pedraza-Díaz S, Lacasaña M, Gonzalez Alzaga B, Lermen D, Bartel-Steinbach M, Katsonouri A, Fiddicke U, Castaño A, Kolossa-Gehring, M. A step towards harmonising human biomonitoring study setup on European level: Materials provided and lessons learnt in HBM4EU. Int J Hyg Environ Health. 249. 114118. 2023.
DOICoordination of chemical analyses under the European Human Biomonitoring Initiative (HBM4EU): Concepts, procedures and lessons learnt.
Vorkamp K, Esteban Lopez M, Gilles L, Göen T, Govarts E, Hajeb P, Katsonouri A, Knudsen LE, Kolossa-Gehring M, Lindh C, Nübler S, Pedraza-Díaz S, Santonen T, Castaño A. Coordination of chemical analyses under the European Human Biomonitoring Initiative (HBM4EU): Concepts, procedures and lessons learnt. Int J Hyg Environ Health.251:114183.2023.
DOIA simple method for direct mercury análisis in dried blood spot (DBS) simples for human biomonitoring studies
Gonzalez-Rubio JM, Dominguez-Morueco N, Pedraza-Díaz S, Cañas-Portilla A, Lucena MA, Rodriguez A, Castaño A, Esteban-López M. A simple method for direct mercury análisis in dried blood spot (DBS) simples for human biomonitoring studies. Environ Int. 177. 107958. 2023.
DOIHBM4EU-MOM: Prenatal methylmercury-exposure control in five countries through suitable dietary advice for pregnancy – Study design and characteristics of participants
Katsonouri A, Gabriel C, Esteban López M, Namorado S, Halldorsson TI, Tratnik J, Rodriguez Martin L, Karakoltzidis A, Chatzimpaloglou A, Giannadaki D, Anastasi E, Thoma A, Domínguez-Morueco N, Cañas Portilla AI, Jacobsen E, Assunçao R, Peres P, Santiago S, Nunes C, Pedraza-Diaz S, Iavicoli I, Leso V, Lacasaña M, González-Alzaga B, Horvat M, Sepai O, Castano A, Kolossa-Gehring M, Karakitsios S, Sarigiannis D. HBM4EU-MOM: Prenatal methylmercury-exposure control in five countries through suitable dietary advice for pregnancy – Study design and characteristics of participants. Int J Hyg Environ Health. 252. 114213. 2023.
DOIApplication of human biomonitoring data to support policy development, raise awareness and environmental public health protection among countries within the HBM4EU project.
Ubong D, Stewart L, Sepai O, Knudsen LE, Berman T, Reynders H, Van Campenhout K, Katsonouri A, Van Nieuwenhuyse A, Ingelido AM, Castaño A, Pedraza-Díaz S, Eiríksdóttir ÁV, Thomsen C, Hartmann C, Gjorgjev D, De Felip E, Tolonen H, Santonen T, klanova J, Norström K, Kononenko L, Silva MJ, Uhl M, Kolossa-Gehring M, Apel P, Jõemaa M, Jajcaj M, Estokova M, Luijten M, Lebret E, von Goetz N, Holcer NJ, Probst-Hensch N, Cavaleiro R, Barouki R, Tarroja E, Balčienė RM, Strumylaite L, Latvala S, Namorado S, Szigeti T, Ingi Halldorsson T, Olafsdottir K, Wasowicz W, Contributors: Viegas S, Alvito P. Application of human biomonitoring data to support policy development, raise awareness and environmental public health protection among countries within the HBM4EU project. International Journal of Hygiene and Environmental Health. 251. 114170. 2023.
DOIHow to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU
Santonen T, Mahiout S, Alvito P, Apel P, Bessems J, Bil W, Borges T, Bose-O'Reilly S, Buekers J, Cañas Portilla AI, Calvo AC, de Alba González M, Domínguez-Morueco N, López ME, Falnoga I, Gerofke A, Caballero MDCG, Horvat M, Huuskonen P, Kadikis N, Kolossa-Gehring M, Lange R, Louro H, Martins C, Meslin M, Niemann L, Díaz SP, Plichta V, Porras SP, Rousselle C, Scholten B, Silva MJ, Šlejkovec Z, Tratnik JS, Joksić AŠ, Tarazona JV, Uhl M, Van Nieuwenhuyse A, Viegas S, Vinggaard AM, Woutersen M, Schoeters G. How to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU. International Journal of Hygiene and Environmental Health. 249. 114139. 2023.
DOIAssociation of exposure to perfluoroalkyl substances (PFAS) and phthalates with thyroid hormones in adolescents from HBM4EU aligned studies.
Rodríguez-Carrillo A, Salamanca-Fernández E, den Hond E, Verheyen VJ, Fábelová L, Murinova LP, Pedraza-Díaz S, Castaño A, García-Lario JV, Remy S, Govarts E, Schoeters G, Olea N, Freire C, Fernández MF. Association of exposure to perfluoroalkyl substances (PFAS) and phthalates with thyroid hormones in adolescents from HBM4EU aligned studies. Environmental Research. 237. 116897. 2023.
DOIIdentification of Real-Life Mixtures Using Human Biomonitoring Data: A Proof of Concept Study
Rodriguez Martin L, Ottenbros I, Vogel N, Kolossa-Gehring M, Schmidt P, Řiháčková K, Juliá Molina M, Varea-Jiménez E, Govarts E, Pedraza-Diaz S, Lebret E, Vlaanderen J, Luijten M. Identification of Real-Life Mixtures Using Human Biomonitoring Data: A Proof of Concept Study. Toxics. 11. 204. 2023
DOIAssessment of exposure to pesticide mixtures in five European countries by a harmonized urinary suspect screening approach
Ottenbros I, Lebret E, Huber C, Lommen A, Antignac J-P, Čupr P, Šulc L, Mikeš O, Szigeti T, Középesy S, Martinsone I, Martinsone Z, Akulova L, Pardo O, Fernández SF, Coscollá C, Pedraza-Diaz S, Krauss M, Debrauwer L, Wagner K, Nijssen R, Mol H, Vitale CM, Klanova J, Molina BG, León N, Vermeulen R, Luijten M, Vlaanderen Assessment of exposure to pesticide mixtures in five European countries by a harmonized urinary suspect screening approach. International Journal of Hygiene and Environmental Health. 248. 114105. 2023.
DOICognitive Performance and Organophosphate Flame Retardants Exposure in Children: Evidence from a cross-sectional analysis of two European mother-child cohorts.
Rosolen V, Giordani E, Mariuz M, Parpinel M, Mustieles V, Gilles L, Govarts E, Rodriguez-Martin L, Baken K, Schoeters G, Sepai O, Sovcikova E, Fabelova L, Kohoutek J, Jensen Tk, Covaci A, Roggeman M, Melymuk L, Klanova J, Castaño A, Esteban López M. Cognitive Performance and Organophosphate Flame Retardants Exposure in Children: Evidence from a cross-sectional analysis of two European mother-child cohorts. Toxics. 11. 878. 2023.
PUBMED DOIMain achievements from the European Human Biomonitoring Initiative HBM4EU.
Gerofke A, Lange R, Vogel N, Schmidt P, Weber T, David M, Frederiksen H, Baken K, Govarts E, Gilles L, Rodriguez Martin L, Martinsone Z, Santonen T, Schoeters G, Scheringer M, Domínguez-Romero E, Esteban López M, Castaño Calvo A, Koch HM, Apel P, Kolossa-Gehring M. Phthalates and substitute plasticizers: Main achievements from the European Human Biomonitoring Initiative HBM4EU. Int J Hyg Environ Health. 259. 114378. 2024.
PUBMED DOIUrinary phthalate/DINCH metabolites associations with kisspeptin and reproductive hormones in teenagers: A cross-sectional study from the HBM4EU aligned studies
Rodriguez-Carrillo A, Remy S, Koppen G, Wauters N, Mustieles V, Desalegn A, Iszatt N, den Hond E, Verheyen VJ, Fabelova L, Palkovicova Murinova L, Pedraza-Diaz S, Esteban M, Poyatos RM, Govarts E, van Nuijs ALN, Covaci A, Schoeters G, Olea N, Fernandez MF. Urinary phthalate/DINCH metabolites associations with kisspeptin and reproductive hormones in teenagers: A cross-sectional study from the HBM4EU aligned studies. Sci Total Environ. 929:171226
DOIUtilización del método de carbón activo para medidas rápidas de radón en viviendas. Revista de Salud Ambiental
M. E. Veiga Ochoa, L. Sánchez Ramos, I. Panero Frade. Utilización del método de carbón activo para medidas rápidas de radón en viviendas. Revista de Salud Ambiental. 2022; 22(2): 143-149.
DOIEstudio estadístico de la actividad desarrollada en la Unidad de Dosimetría Ambiental y Personal del Servicio de Radioprotección del Centro Nacional de Sanidad Ambiental
C Ruiz Gimeno, J Moracho, L Sánchez, C Ballesteros, P Medina, J Castro. Estudio estadístico de la actividad desarrollada en la Unidad de Dosimetría Ambiental y Personal del Servicio de Radioprotección del Centro Nacional de Sanidad Ambiental. RADIOPROTECCIÓN 84 (2016).
PUBMEDApproaches to mixture risk assessment of PFASs in the European population based on human hazard and biomonitoring data
Bil W, Govarts E, Zeilmaker MJ, Woutersen M, Bessems J, Ma Y, Thomsen C, Haug LS, Lignell S, Gyllenhammar I, Palkovicova Murinova L, Fabelova L, Snoj Tratnik J, Kosjek T, Gabriel C, Sarigiannis D, Pedraza-Diaz S, Esteban-López M, Castaño A, Rambaud L, Riou M, Franken C, Colles A, Vogel N, Kolossa-Gehring M, Halldorsson TI, Uhl M, Schoeters G, Santonen T, Vinggaard AM. Approaches to mixture risk assessment of PFASs in the European population based on human hazard and biomonitoring data. Int J Hyg Environ Health. 247: 114071. 2022.
DOICross-sectional associations between exposure to per- and polyfluoroalkyl substances and body mass index among European teenagers in the HBM4EU aligned studies
Schillemans T, Iszatt N, Remy S, Schoeters G, Fernandez MF, D’Cruz SC, Desalegn A, Haug LS, Lignell S, Lindroos AK, Fabelova L, Palkovicova Murinova L, Kosjek T, Tkalec Z, Gabriel C, Sarigiannis D, Pedraza-Díaz S, Esteban-Lopez M, Castaño A, Rambaud L, Riou M, Pauwels S, Vanlarebeke N, Kolossa-Gehring M, Vogel N, Uhl M, Govarts E, Åkesson A. Cross-sectional associations between exposure to per- and polyfluoroalkyl substances and body mass index among European teenagers in the HBM4EU aligned studies. Environ Pollut. 316: 120566. 2022.
DOIInterpreting biomonitoring data: Introducing the international human biomonitoring (i-HBM) working Group's health-based guidance value (HB2GV) dashboard
Nakayama SF, St-Amand A, Pollock T, Apel P, Bamai YA, Barr DB, Bessems J, Calafat AM, Castaño A, Covaci A, Duca RC, Faure S, Galea KS, Hays S, Hopf NB, Ito Y, Zare Jeddi M, Kolossa-Gehring M, Kumar E, LaKind JS, Esteban Lopez M, Louro H, Macey K, Makris KC, Melnyk L, Murawski A, Naiman J, Nassif J, Noisel N, Poddalgoda D, Quiros-Alcala L, Rafiee A, Rambaud L, Silva MJ, Ueyama J, Verner MA, Nasution Waras M, Werry K. Interpreting biomonitoring data: Introducing the international human biomonitoring (i-HBM) working Group's health-based guidance value (HB2GV) dashboard. Int J Hyg Environ Health. 247: 114046. 2022.
DOIContenidos con Investigacion .
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José Vicente Tarazona Lafarga
Jefe de Grupo. Profesor de Investigación de OPI
Código ORCID: 0000-0003-4920-3055
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Listado de personal
Información adicional
La Unidad de Evaluación de Riesgo se creó como una unidad horizontal del CNSA en octubre de 2022, aprovechando la experiencia de investigadores del centro en evaluación de riesgos de plaguicidas y otras sustancias químicas, y la incorporación de nuevos investigadores. Nuestra misión es proporcionar una evaluación científica rigurosa y objetiva de los riesgos que las sustancias químicas pueden representar para las personas y el medio ambiente en diversas condiciones de exposición, en el marco de la aproximación “One Health”. La unidad ofrece a las diferentes Áreas del CNSA, así como a otros grupos del ISCIII interesados, una plataforma o “Laboratorio de Ideas” para obtener un valor añadido a sus resultados, mediante metodologías innovadoras de evaluación de riesgos.