Protegemos tu salud a través de la Ciencia
Investigación
Salud urbana: calidad del aire, salud y bienestar en entornos urbanos
Líneas de investigación
Contenidos con Investigacion .
Salud urbana: calidad del aire, salud y bienestar en entornos urbanos
1- Laboratorios Ciudadanos Urbanos (ULL) para abordar el estudio de las exposiciones ambientales.
La participación ciudadana en proyectos de investigación es fundamental para identificar determinantes de salud urbanos y diseñar intervenciones tanto a nivel individual como urbano que mejoren el bienestar y la calidad de vida de la población. A su vez, nos permite realizar campañas de biomonitorización humana para estudiar los efectos de las exposiciones ambientales como la contaminación atmosférica, ruido o luz en el desarrollo de enfermedades no comunicables entre otras enfermedades respiratorias, cardiovasculares o neurodegenerativas, así como otros trastornos relacionados con el sueño, o la salud mental.
PROYECTOS:
- Proyecto Europeo Horizonte Europa ENVESOME: The ENVironmental ExpoSOME and health”. www.envesome.eu.
Financiado HORIZON-HLTH-2024-ENVHLTH-02-06. Duración 4 años: diciembre 2024- noviembre 2028. IP ISCIII: Dra. Beatriz Núñez Corcuera
- Proyecto Europeo H2020 URBANOME “URBAN Observatory for multiparticipatory enhancement of wellbeing and health”, Ga 945391. www.urbanome.ue. Duración 4 años: marzo 2021- agosto 2025 IP ISCIII: Dra. Beatriz Núñez Corcuera
2- Estudio de la exposición a contaminantes atmosféricos urbanos: Material Particulado, Óxidos de nitrógeno y Ozono en poblaciones vulnerables. Exposiciones prenatales y Efectos Adversos al Nacimiento.
Esta línea de investigación aborda el estudio de los efectos adversos al nacimiento atribuibles a la exposición de contaminantes atmosféricos urbanos durante el embarazo. Combina el análisis de datos de contaminación atmosférica proporcionados por organismos de referencia con modelización y estudios epidemiológicos. Esta línea se desarrolla en colaboración con la Dra. Rebeca Ramis Prieto. Área de Epidemiologia de Cáncer y Ambiental. CNE_ISCIII. ORCID: 0000-0001-6154-9142.
PROYECTOS:
QALIOPE ; Calidad de aire, cambio climático y espacios verdes.
Financiado por Acción Estratégica en Salud Intramural (AESI) 2024. Duración 3 años. IP Dra. Rebeca Ramis Prieto, Co-IP Dra. Beatriz Nuñez Corcuera
Publicaciones destacadas
A Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Using Human Biomonitoring Data.
1. Tarazona, J. V., Cattaneo, I., Niemann, L., Pedraza-Diaz, S., González-Caballero, M. C., de Alba-Gonzalez, M., Cañas, A., Dominguez-Morueco, N., Esteban-López, M., Castaño, A., Borges, T., Katsonouri, A., Makris, K. C., Ottenbros, I., Mol, H., De Decker, A., Morrens, B., Berman, T., Barnett-Itzhaki, Z., … Santonen, T. (2022). A Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Using Human Biomonitoring Data. Toxics 2022, Vol. 10, Page 451, 10(8), 451.
DOIApplicability of Food Monitoring Data for Assessing Relative Exposure Contributions of Pyrethroids in Retrospective Human Biomonitoring Risk Estimations.
2. de Alba-Gonzalez, M., González-Caballero, M. C., & Tarazona, J. V. (2024). Applicability of Food Monitoring Data for Assessing Relative Exposure Contributions of Pyrethroids in Retrospective Human Biomonitoring Risk Estimations. Toxics, 12(1), 24.
DOIHow to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU.
3. Santonen, T., Mahiout, S., Alvito, P., Apel, P., Bessems, J., Bil, W., Borges, T., Bose-O’Reilly, S., Buekers, J., Cañas Portilla, A. I., Calvo, A. C., de Alba González, M., Domínguez-Morueco, N., López, M. E., Falnoga, I., Gerofke, A., Caballero, M. del C. G., Horvat, M., Huuskonen, P., … Schoeters, G. (2023). How to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU. International Journal of Hygiene and Environmental Health, 249, 114139.
DOIImproving the Risk Assessment of Pesticides through the Integration of Human Biomonitoring and Food Monitoring Data: A Case Study for Chlorpyrifos.
4. Tarazona, J. V., González-Caballero, M. D. C., de Alba-Gonzalez, M., Pedraza-Diaz, S., Cañas, A., Dominguez-Morueco, N., Esteban-López, M., Cattaneo, I., Katsonouri, A., Makris, K. C., Halldorsson, T. I., Olafsdottir, K., Zock, J. P., Dias, J., De Decker, A., Morrens, B., Berman, T., Barnett-Itzhaki, Z., Lindh, C., … Castaño, A. (2022). Improving the Risk Assessment of Pesticides through the Integration of Human Biomonitoring and Food Monitoring Data: A Case Study for Chlorpyrifos. Toxics, 10(6), 313.
DOIMethylmercury Risk Assessment Based on European Human Biomonitoring Data.
5. Domínguez-Morueco, N., Pedraza-Díaz, S., González-Caballero, M. del C., Esteban-López, M., de Alba-González, M., Katsonouri, A., Santonen, T., Cañas-Portilla, A., & Castaño, A. (2022). Methylmercury Risk Assessment Based on European Human Biomonitoring Data. Toxics, 10(8), 427.
DOIPollution, indoor air.
6. González-Caballero, M. del Carmen, de Alba-Gonzalez, M., & Tarazona, J. V. (2024). Pollution, indoor air. Encyclopedia of Toxicology, Fourth Edition: Volume 1-9, 7, 787–799.
DOIEvaluating urban indoor and outdoor PM10-bound organochlorine pesticides. Air quality status and health impact.
7. Galán-Madruga, D., Cárdenas-Escudero, J., Broomandi, P., Cáceres, J. O., & González, M. D. C. (2023). Evaluating urban indoor and outdoor PM10-bound organochlorine pesticides. Air quality status and health impact. Building and Environment, 228, 109818.
DOIInternalization and toxicity of polystyrene nanoplastics on inmortalized human neural stem cells.
8. González-Caballero, M. C., de Alba González, M., Torres-Ruiz, M., Iglesias-Hernández, P., Zapata, V., Terrón, M. C., Sachse, M., Morales, M., Martin-Folgar, R., Liste, I., & Cañas-Portilla, A. I. (2024). Internalization and toxicity of polystyrene nanoplastics on inmortalized human neural stem cells. Chemosphere, 355, 141815.
DOINeurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo.
9. Torres-Ruiz, M., de Alba González, M., Morales, M., Martin-Folgar, R., González, M. C., Cañas-Portilla, A. I., & De la Vieja, A. (2023). Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo. Science of The Total Environment, 874, 162406.
DOIHuman neural stem cells in developmental neurotoxicology: Current scenario and future prospects.
10. Rosca, A., Coronel, R., López-Alonso, V., Liste, I., & González-Caballero, M. C. (2023). Human neural stem cells in developmental neurotoxicology: Current scenario and future prospects. Advances in Neurotoxicology, 9, 197–237.
DOIEffects of 700 and 3500 MHz 5G radiofrequency exposure on developing zebrafish embryos.
Torres-Ruiz, M; Oscar J. Suárez; Victoria López; Pablo Marina; Aránzazu Sanchis; Isabel Liste; Mercedes de Alba; Victoria Ramos. 2024. Effects of 700 and 3500 MHz 5G radiofrequency exposure on developing zebrafish embryos. Science of the Total Environment. 169475.
DOIEffects of nanomolar methylmercury on developing human neural stem cells and zebrafish Embryo
Torres-Ruiz, M; De Alba, M; Coronel, R; Liste, I; Cañas, AI; Gonzalez, M. 2024. Effects of nanomolar methylmercury on developing human neural stem cells and zebrafish Embryo. Food Chem Toxicol. 188:114684.
DOINew approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project.
Tal T, Myhre O, Fritsche E, ….., Torres-Ruiz M, and Bartmann K (2024) New approach methods to assess developmental and adult neurotoxicity for regulatory use: a PARC work package 5 project. Front. Toxicol. 6:1359507.
DOIInternalization and toxicity of polystyrene nanoplastics on immortalized human neural stem cells
Mª. Carmen González-Caballero; Mercedes de Alba González; Mónica Torres-Ruiz; Ana I. Cañas-Portilla; Patricia Iglesias-Hernandez. Internalization and toxicity of polystyrene nanoplastics on immortalized human neural stem cells. Chemosphere 29:355:141815 2024.
DOINeurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo.
Mónica Torres-Ruiz, Mercedes de Alba González, Mónica Morales, Raquel Martin-Folgar, Mª Carmen González, Ana I. Cañas-Portilla*, and Antonio De la Vieja* 2023 Neurotoxicity and endocrine disruption caused by polystyrene nanoparticles in zebrafish embryo. Science of the Total Environment, 2023 May 20;874:162406.
DOIMolecular effects of polystyrene nanoplastics on human neural stem cells
Raquel Martin-Folgar, Mª Carmen González-Caballero, Mónica Torres-Ruíz, Ana I. Cañas-Portilla, Mercedes de Alba-González, Isabel Liste, Mónica Morales. Molecular effects of polystyrene nanoplastics on human neural stem cells PLOS ONE, enero 2024.
DOIDNA damage and molecular level effects induced by polystyrene (PS) nanoplastics (NPs) after Chironomus riparius (Diptera) larvae
Raquel Martin-Folgar, Celia Sabroso, Ana I. Cañas-Portilla, Mónica Torres-Ruíz, Mª Carmen González-Caballero, Helena Dorado, Ignacio Velasco, Mónica Morales. DNA damage and molecular level effects induced by polystyrene (PS) nanoplastics (NPs) after Chironomus riparius (Diptera) larvae. Chemosphere 346 (2024) 140552
DOINew approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project. Frontiers in Toxicology
Louise Ramhøj, Marta Axelstad, Yoni Baert, Ana I. Cañas-Portilla, Frédéric Chalmel, Lars Dahmen, Antonio De La Vieja, Bertrand Evrard, Ann-Cathrin Haigis, Timo Hamers, Kim Heikamp, Henrik Holbech, Patricia Iglesias-Hernandez, Dries Knapen, Lorna Marchandise, Jane E. Morthorst, Nikolai Georgiev Nikolov, Ana C. V. E. Nissen, Michael Oelgeschlaeger, Kostja Renko, Vera Rogiers, Gerrit Schüürmann, Evelyn Stincken, Mette H. Stub, Monica Torres-Ruiz, Majorie Van Duursen, Tamara Vanhaeck, Lucia Vergauwen, Eva Bay Wedebye, Terje Svingen. New approach methods to improve human health risk assessment of thyroid hormone system disruption–a PARC project. Frontiers in Toxicology. 2023
DOIMolecular effects of polystyrene nanoplastics toxicity in zebrafish embryos (Danio rerio)
Raquel Martin-Folgar, Mónica Torres-Ruiz, Mercedes de Alba, Ana I. Cañas-Portilla, Mª Carmen González, Mónica Morales. Molecular effects of polystyrene nanoplastics toxicity in zebrafish embryos (Danio rerio) Chemosphere, 2023 Jan;312(Pt 1):137077.
DOIToxicity of nanoplastics for zebrafish embryos, what we know and where to go next.
Torres-Ruiz,M.; De la Vieja,A.; De Alba Gonzalez,M.; Esteban Lopez,M.; Castaño,A.; Cañas Portilla, A.I.; 2021. Toxicity of nanoplastics for zebrafish embryos, what we know and where to go next. Science of the Total Environment 797: 149125.
DOIHuman urinary arsenic species, associated exposure determinants and potential health risks assessed in the HBM4EU Aligned Studies
Buekers J, Baken K, Govarts E, Rodriguez Martin L, Vogel N, Kolossa-Gehring M, Šlejkovec Z, Falnoga I, Horvat M, Lignell S, Lindroos AK, Rambaud L, Riou M, Pedraza-Diaz S, Esteban-Lopez M, Castaño A, Den Hond E, Baeyens W, Santonen T, Schoeters G. Human urinary arsenic species, associated exposure determinants and potential health risks assessed in the HBM4EU Aligned Studies. Int J Hyg Environ Health. 248: 114115. 2023.
DOILiterature review and evaluation of biomarkers, matrices and analytical methods for chemicals selected in the research program Human Biomonitoring for the European Union (HBM4EU)
Sabbioni G, Castaño A, Esteban López M, Göen T, Mol H, Riou M, Tagne-Fotso R. Literature review and evaluation of biomarkers, matrices and analytical methods for chemicals selected in the research program Human Biomonitoring for the European Union (HBM4EU). Environ Int. 169: 107458. 2022.
DOIHarmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014-2021).
Govarts E, Gilles L, Rodriguez-Martin L, Santonene T, Apel P, Alvito P, Anastasi E, et al. Harmonized human biomonitoring in European children, teenagers and adults: EU-wide exposure data of 11 chemical substance groups from the HBM4EU Aligned Studies (2014-2021). Int J Hyg Environ Health. 249.114119. 2023.
DOIA step towards harmonising human biomonitoring study setup on European level: Materials provided and lessons learnt in HBM4EU.
Pack LK, Gilles L, Cops J, Tolonen H, van Kamp I, Esteban-Lopez M, Pedraza-Díaz S, Lacasaña M, Gonzalez Alzaga B, Lermen D, Bartel-Steinbach M, Katsonouri A, Fiddicke U, Castaño A, Kolossa-Gehring, M. A step towards harmonising human biomonitoring study setup on European level: Materials provided and lessons learnt in HBM4EU. Int J Hyg Environ Health. 249. 114118. 2023.
DOICoordination of chemical analyses under the European Human Biomonitoring Initiative (HBM4EU): Concepts, procedures and lessons learnt.
Vorkamp K, Esteban Lopez M, Gilles L, Göen T, Govarts E, Hajeb P, Katsonouri A, Knudsen LE, Kolossa-Gehring M, Lindh C, Nübler S, Pedraza-Díaz S, Santonen T, Castaño A. Coordination of chemical analyses under the European Human Biomonitoring Initiative (HBM4EU): Concepts, procedures and lessons learnt. Int J Hyg Environ Health.251:114183.2023.
DOIA simple method for direct mercury análisis in dried blood spot (DBS) simples for human biomonitoring studies
Gonzalez-Rubio JM, Dominguez-Morueco N, Pedraza-Díaz S, Cañas-Portilla A, Lucena MA, Rodriguez A, Castaño A, Esteban-López M. A simple method for direct mercury análisis in dried blood spot (DBS) simples for human biomonitoring studies. Environ Int. 177. 107958. 2023.
DOIHBM4EU-MOM: Prenatal methylmercury-exposure control in five countries through suitable dietary advice for pregnancy – Study design and characteristics of participants
Katsonouri A, Gabriel C, Esteban López M, Namorado S, Halldorsson TI, Tratnik J, Rodriguez Martin L, Karakoltzidis A, Chatzimpaloglou A, Giannadaki D, Anastasi E, Thoma A, Domínguez-Morueco N, Cañas Portilla AI, Jacobsen E, Assunçao R, Peres P, Santiago S, Nunes C, Pedraza-Diaz S, Iavicoli I, Leso V, Lacasaña M, González-Alzaga B, Horvat M, Sepai O, Castano A, Kolossa-Gehring M, Karakitsios S, Sarigiannis D. HBM4EU-MOM: Prenatal methylmercury-exposure control in five countries through suitable dietary advice for pregnancy – Study design and characteristics of participants. Int J Hyg Environ Health. 252. 114213. 2023.
DOIApplication of human biomonitoring data to support policy development, raise awareness and environmental public health protection among countries within the HBM4EU project.
Ubong D, Stewart L, Sepai O, Knudsen LE, Berman T, Reynders H, Van Campenhout K, Katsonouri A, Van Nieuwenhuyse A, Ingelido AM, Castaño A, Pedraza-Díaz S, Eiríksdóttir ÁV, Thomsen C, Hartmann C, Gjorgjev D, De Felip E, Tolonen H, Santonen T, klanova J, Norström K, Kononenko L, Silva MJ, Uhl M, Kolossa-Gehring M, Apel P, Jõemaa M, Jajcaj M, Estokova M, Luijten M, Lebret E, von Goetz N, Holcer NJ, Probst-Hensch N, Cavaleiro R, Barouki R, Tarroja E, Balčienė RM, Strumylaite L, Latvala S, Namorado S, Szigeti T, Ingi Halldorsson T, Olafsdottir K, Wasowicz W, Contributors: Viegas S, Alvito P. Application of human biomonitoring data to support policy development, raise awareness and environmental public health protection among countries within the HBM4EU project. International Journal of Hygiene and Environmental Health. 251. 114170. 2023.
DOIHow to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU
Santonen T, Mahiout S, Alvito P, Apel P, Bessems J, Bil W, Borges T, Bose-O'Reilly S, Buekers J, Cañas Portilla AI, Calvo AC, de Alba González M, Domínguez-Morueco N, López ME, Falnoga I, Gerofke A, Caballero MDCG, Horvat M, Huuskonen P, Kadikis N, Kolossa-Gehring M, Lange R, Louro H, Martins C, Meslin M, Niemann L, Díaz SP, Plichta V, Porras SP, Rousselle C, Scholten B, Silva MJ, Šlejkovec Z, Tratnik JS, Joksić AŠ, Tarazona JV, Uhl M, Van Nieuwenhuyse A, Viegas S, Vinggaard AM, Woutersen M, Schoeters G. How to use human biomonitoring in chemical risk assessment: Methodological aspects, recommendations, and lessons learned from HBM4EU. International Journal of Hygiene and Environmental Health. 249. 114139. 2023.
DOIAssociation of exposure to perfluoroalkyl substances (PFAS) and phthalates with thyroid hormones in adolescents from HBM4EU aligned studies.
Rodríguez-Carrillo A, Salamanca-Fernández E, den Hond E, Verheyen VJ, Fábelová L, Murinova LP, Pedraza-Díaz S, Castaño A, García-Lario JV, Remy S, Govarts E, Schoeters G, Olea N, Freire C, Fernández MF. Association of exposure to perfluoroalkyl substances (PFAS) and phthalates with thyroid hormones in adolescents from HBM4EU aligned studies. Environmental Research. 237. 116897. 2023.
DOIIdentification of Real-Life Mixtures Using Human Biomonitoring Data: A Proof of Concept Study
Rodriguez Martin L, Ottenbros I, Vogel N, Kolossa-Gehring M, Schmidt P, Řiháčková K, Juliá Molina M, Varea-Jiménez E, Govarts E, Pedraza-Diaz S, Lebret E, Vlaanderen J, Luijten M. Identification of Real-Life Mixtures Using Human Biomonitoring Data: A Proof of Concept Study. Toxics. 11. 204. 2023
DOIAssessment of exposure to pesticide mixtures in five European countries by a harmonized urinary suspect screening approach
Ottenbros I, Lebret E, Huber C, Lommen A, Antignac J-P, Čupr P, Šulc L, Mikeš O, Szigeti T, Középesy S, Martinsone I, Martinsone Z, Akulova L, Pardo O, Fernández SF, Coscollá C, Pedraza-Diaz S, Krauss M, Debrauwer L, Wagner K, Nijssen R, Mol H, Vitale CM, Klanova J, Molina BG, León N, Vermeulen R, Luijten M, Vlaanderen Assessment of exposure to pesticide mixtures in five European countries by a harmonized urinary suspect screening approach. International Journal of Hygiene and Environmental Health. 248. 114105. 2023.
DOICognitive Performance and Organophosphate Flame Retardants Exposure in Children: Evidence from a cross-sectional analysis of two European mother-child cohorts.
Rosolen V, Giordani E, Mariuz M, Parpinel M, Mustieles V, Gilles L, Govarts E, Rodriguez-Martin L, Baken K, Schoeters G, Sepai O, Sovcikova E, Fabelova L, Kohoutek J, Jensen Tk, Covaci A, Roggeman M, Melymuk L, Klanova J, Castaño A, Esteban López M. Cognitive Performance and Organophosphate Flame Retardants Exposure in Children: Evidence from a cross-sectional analysis of two European mother-child cohorts. Toxics. 11. 878. 2023.
PUBMED DOIMain achievements from the European Human Biomonitoring Initiative HBM4EU.
Gerofke A, Lange R, Vogel N, Schmidt P, Weber T, David M, Frederiksen H, Baken K, Govarts E, Gilles L, Rodriguez Martin L, Martinsone Z, Santonen T, Schoeters G, Scheringer M, Domínguez-Romero E, Esteban López M, Castaño Calvo A, Koch HM, Apel P, Kolossa-Gehring M. Phthalates and substitute plasticizers: Main achievements from the European Human Biomonitoring Initiative HBM4EU. Int J Hyg Environ Health. 259. 114378. 2024.
PUBMED DOIUrinary phthalate/DINCH metabolites associations with kisspeptin and reproductive hormones in teenagers: A cross-sectional study from the HBM4EU aligned studies
Rodriguez-Carrillo A, Remy S, Koppen G, Wauters N, Mustieles V, Desalegn A, Iszatt N, den Hond E, Verheyen VJ, Fabelova L, Palkovicova Murinova L, Pedraza-Diaz S, Esteban M, Poyatos RM, Govarts E, van Nuijs ALN, Covaci A, Schoeters G, Olea N, Fernandez MF. Urinary phthalate/DINCH metabolites associations with kisspeptin and reproductive hormones in teenagers: A cross-sectional study from the HBM4EU aligned studies. Sci Total Environ. 929:171226
DOIUtilización del método de carbón activo para medidas rápidas de radón en viviendas. Revista de Salud Ambiental
M. E. Veiga Ochoa, L. Sánchez Ramos, I. Panero Frade. Utilización del método de carbón activo para medidas rápidas de radón en viviendas. Revista de Salud Ambiental. 2022; 22(2): 143-149.
DOIEstudio estadístico de la actividad desarrollada en la Unidad de Dosimetría Ambiental y Personal del Servicio de Radioprotección del Centro Nacional de Sanidad Ambiental
C Ruiz Gimeno, J Moracho, L Sánchez, C Ballesteros, P Medina, J Castro. Estudio estadístico de la actividad desarrollada en la Unidad de Dosimetría Ambiental y Personal del Servicio de Radioprotección del Centro Nacional de Sanidad Ambiental. RADIOPROTECCIÓN 84 (2016).
PUBMEDApproaches to mixture risk assessment of PFASs in the European population based on human hazard and biomonitoring data
Bil W, Govarts E, Zeilmaker MJ, Woutersen M, Bessems J, Ma Y, Thomsen C, Haug LS, Lignell S, Gyllenhammar I, Palkovicova Murinova L, Fabelova L, Snoj Tratnik J, Kosjek T, Gabriel C, Sarigiannis D, Pedraza-Diaz S, Esteban-López M, Castaño A, Rambaud L, Riou M, Franken C, Colles A, Vogel N, Kolossa-Gehring M, Halldorsson TI, Uhl M, Schoeters G, Santonen T, Vinggaard AM. Approaches to mixture risk assessment of PFASs in the European population based on human hazard and biomonitoring data. Int J Hyg Environ Health. 247: 114071. 2022.
DOICross-sectional associations between exposure to per- and polyfluoroalkyl substances and body mass index among European teenagers in the HBM4EU aligned studies
Schillemans T, Iszatt N, Remy S, Schoeters G, Fernandez MF, D’Cruz SC, Desalegn A, Haug LS, Lignell S, Lindroos AK, Fabelova L, Palkovicova Murinova L, Kosjek T, Tkalec Z, Gabriel C, Sarigiannis D, Pedraza-Díaz S, Esteban-Lopez M, Castaño A, Rambaud L, Riou M, Pauwels S, Vanlarebeke N, Kolossa-Gehring M, Vogel N, Uhl M, Govarts E, Åkesson A. Cross-sectional associations between exposure to per- and polyfluoroalkyl substances and body mass index among European teenagers in the HBM4EU aligned studies. Environ Pollut. 316: 120566. 2022.
DOIInterpreting biomonitoring data: Introducing the international human biomonitoring (i-HBM) working Group's health-based guidance value (HB2GV) dashboard
Nakayama SF, St-Amand A, Pollock T, Apel P, Bamai YA, Barr DB, Bessems J, Calafat AM, Castaño A, Covaci A, Duca RC, Faure S, Galea KS, Hays S, Hopf NB, Ito Y, Zare Jeddi M, Kolossa-Gehring M, Kumar E, LaKind JS, Esteban Lopez M, Louro H, Macey K, Makris KC, Melnyk L, Murawski A, Naiman J, Nassif J, Noisel N, Poddalgoda D, Quiros-Alcala L, Rafiee A, Rambaud L, Silva MJ, Ueyama J, Verner MA, Nasution Waras M, Werry K. Interpreting biomonitoring data: Introducing the international human biomonitoring (i-HBM) working Group's health-based guidance value (HB2GV) dashboard. Int J Hyg Environ Health. 247: 114046. 2022.
DOIPFAS levels and determinants of variability in exposure in European teenagers – Results from the HBM4EU aligned studies (2014-2021)
Richterova D, Govarts E, Fabelova L, Rausova K, Rodriguez Martin L, Gilles L, Remy S, Colles A, Rambaud L, Riou M, Gabriel C, Sarigiannis D, Pedraza-Diaz S, Ramos JJ, Kosjek T, Snoj Tratnik J, Lignell S, Gyllenhammar I, Thomsen C, Haug LS, Kolossa-Gehring M, Vogel N, Franken C, Vanlarebeke N, Bruckers L, Stewart L, Sepai O, Schoeters G, Uhl M, Castaño A, Esteban López M, Göen T, Palkovicova Murínova P. PFAS levels and determinants of variability in exposure in European teenagers – Results from the HBM4EU aligned studies (2014-2021). Int J Hyg Environ Heatlh. 247: 114057. 2022.
DOIExternal Quality Assurance Schemes (EQUASs) and Inter-laboratory Comparison Investigations (ICIs) for human biomonitoring of Polycyclic Aromatic Hydrocarbon (PAH) biomarkers in urine as part of the quality assurance programme under HBM4EU
Stefanie N, Esteban López M, Castaño A, Mol H, Müller J, Schäfer M, Haji-Abbas-Zarrabi K, Hajslova J, Pulkrabova J, Göen T, Dvorakova D, Urbancova K, Koch HM, Antignac JP, Sakhi AK, Vorkamp K, Burkhardt T, Scherer M. External Quality Assurance Schemes (EQUASs) and Inter-laboratory Comparison Investigations (ICIs) for human biomonitoring of Polycyclic Aromatic Hydrocarbon (PAH) biomarkers in urine as part of the quality assurance programme under HBM4EU. 2022.
DOI. Concurrent Assessment of Phthalates/HEXAMOLL (R) DINCH Exposure and Wechsler Intelligence Scale for Children Performance in Three European Cohorts of the HBM4EU Aligned Studies
Rosolen V, Giordani E, Mariuz M, Parpinel M, Ronfani L, Vecchi Brumatti L, Bin M, Calamandrei G, Mustieles V, Gilles L, Govarts E, Baken K, Rodriguez Martin L, Schoeters G, Sepai O, Sovcikova E, Fabelova L, Šidlovská M, Kolena B, Kold Jensen T, Frederiksen H, Kolossa-Gehring M, Lange R, Apel P, Castano A, Esteban López M, Jacobs G, Voorspoels S, Jurdáková H, Górová R, Barbone F. Concurrent Assessment of Phthalates/HEXAMOLL (R) DINCH Exposure and Wechsler Intelligence Scale for Children Performance in Three European Cohorts of the HBM4EU Aligned Studies. Toxics 10: 538. 2022.
DOIGlyphosate and AMPA in Human Urine of HBM4EU-Aligned Studies: Part B Adults
Buekers J, Remy S, Bessems J, Govarts E, Rambaud L, Riou M, Halldorsson TI, Ólafsdóttir K, Probst-Hensch N, Ammann P, Weber T, Kolossa-Gehring M, Esteban-López M, Castaño A, Raun Andersen H, Schoeters G. Glyphosate and AMPA in Human Urine of HBM4EU-Aligned Studies: Part B Adults. Toxics 10: 552. 2022.
DOIGlyphosate and AMPA in Human Urine of HBM4EU-Aligned Studies: Part A Children
Buekers J, Remy S, Bessems J, Govarts E, Rambaud L, Riou M, Snoj Tratnik J, Stajnko A, Katsonouri A, Makris KC, De Decker A, Morrens B, Vogel N, Kolossa-Gehring M, Esteban-López M, Castaño A, Raun Andersen H, Schoeters G. Glyphosate and AMPA in Human Urine of HBM4EU-Aligned Studies: Part A Children. Toxics. 10: 470. 2022.
DOIA Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Using Human Biomonitoring Data
Tarazona JV, Cattaneo I, Niemann L, Pedraza-Diaz S, González-Caballero MC, de Alba-Gonzalez M, Cañas A, Dominguez-Morueco N, Esteban-López M, Castaño A, Borges T, Katsonouri A, Makris KC, Ottenbros I, Mol H, De Decker A, Morrens B, Berman T, Barnett-Itzhaki Z, Probst-Hensch N, Fuhrimann S, Tratnik JS, Horvat M, Rambaud L, Riou M, Schoeters G, Govarts E, Kolossa-Gehring M, Weber T, Apel P, Namorado S, Santonen T. A Tiered Approach for Assessing Individual and Combined Risk of Pyrethroids Using Human Biomonitoring Data. Toxics. 10, 451. 2022.
DOIFrom science to policy: How European HBM indicators help to answer policy questions related to phthalates and DINCH exposure
Gerofke A, David M, Schmidt P, Lobo Vicente J, Buekers J, Gilles L, Colles A, Bessems J, Bastiaensen M, Covaci A, Den Hond E, Koppen G, Laeremans M, Verheyen VJ, Černá M, Klánová J, Krsková A, Zvonař M, Knudsen LE, Koch HM, Rambaud L, Riou M, Vogel N, Gabriel C, Karakitsios S, Papaioannou N, Sarigiannis D, Kakucs R, Középesy S, Rudnai P, Szigeti T, Barbone F, Rosolen V, Guignard C, Gutleb AC, Sakhi AK, Haug LS, Janasik B, Ligocka D, Estokova M, Fabelova L, Kolena B, Palkovicova Murinova L, Petrovicova I, Richterova D, Horvat M, Mazej D, Snoj Tratnik J, Runkel AA, Castaño A, Esteban-López M, Pedraza-Díaz S, Åkesson A, Lignell S, Vlaanderen J, Zock JP, Schoeters G, Kolossa-Gehring M. From science to policy: How European HBM indicators help to answer policy questions related to phthalates and DINCH exposure. Int J Hyg Environ Health. 247: 114073. 2022.
DOICumulative risk assessment of five phthalates in European children and adolescents
Lange R, Vogel N, Schmidt P, Gerofke A, Luijten M, Bil W, Santonen T, Schoeters G, Gilles L, Sakhi AK, Haug LS, Jensen TK, Frederiksen H, Koch HM, Szigeti T, Szabados M, Snoj Tratnik J, Mazej D, Gabriel C, Sarigiannis D, Dzhedzheia V, Karakitsios S, Rambaud L, Riou M, Koppen G, Covaci A, Zvona M, Piler P, Klanova J, Fabelova L, Richterova D, Kosjek T, Runkel A, Pedraza-Díaz S, Verheyen V, Bastiaensen M, Esteban-López M, Castaño A, Kolossa-Gehring M. Cumulative risk assessment of five phthalates in European children and adolescents. Environ J Hyg Environ Health 246: 114052. 2022.
DOIPersonal care product use and lifestyle affect phthalate and DINCH metabolite levels in teenagers and young adults
Fišerová PS, Melymuk L, Komprdová K, Domínguez-Romero E, Scheringer M, Kohoutek J, Přibylová P, Andrýsková L, Piler P, Koch HM, Zvonař M, Esteban-López M, Castaño A, Klánová J. Personal care product use and lifestyle affect phthalate and DINCH metabolite levels in teenagers and young adults. Environ Res. 213:113675. 2022.
DOIImproving the Risk Assessment of Pesticides through the Integration of Human Biomonitoring and Food Monitoring Data: A Case Study for Chlorpyrifos
Tarazona JV, González-Caballero MC, de Alba-Gonzalez M, Pedraza-Diaz S, Cañas A, Dominguez-Morueco N, Esteban-López M, Cattaneo I, Katsonouri A, Makris KC, Halldorsson TI, Olafsdottir K, Zock JP, Dias J, De Decker A, Morrens B, Berman T, Barnett-Itzhaki Z, Lindh C, Gilles L, Govarts E, Schoeters G, Weber T, Kolossa-Gehring M, Santonen T, Castaño A. Improving the Risk Assessment of Pesticides through the Integration of Human Biomonitoring and Food Monitoring Data: A Case Study for Chlorpyrifos. Toxics. 10:313. 2022.
DOIHarmonization of human biomonitoring studies in Europe: characteristics of the HBM4EU aligned studies participants
Gilles L, Govarts E, Rodriguez Martin L, Andersson AM, Appenzeller BMR, Barbone F, Castaño A, Coertjens D, Den Hond E, Dzhedzheia V, Eržen I, Esteban López M, et al. Harmonization of human biomonitoring studies in Europe: characteristics of the HBM4EU aligned studies participants. Int J Environ Res Public Health. 19:6787. 2022.
DOIMethylmercury Risk Assessment Based on European Human Biomonitoring Data
Domínguez-Morueco N, Pedraza-Díaz S, González-Caballero MC, Esteban-López M, Alba-González M, Katsonouri A, Santonen T, Cañas-Portilla A, Castaño A. Methylmercury Risk Assessment Based on European Human Biomonitoring Data. Toxics. 10: 427. 2022.
DOIInterlaboratory Comparison Investigations (ICI) for human biomonitoring of chromium as part of the quality assurance programme under HBM4EU
Nübler S, Esteban López M, Castaño A, Mol HGJ, Haji-Abbas-Zarrabi K, Schäfer M, Müller J, Hajslova J, Dvorakova D, Antignac JP, Koch HM, Småstuen Haug L , Vorkamp K, Göen T. Interlaboratory Comparison Investigations (ICIs) and External Quality Assurance Schemes (EQUASs) for human biomonitoring of perfluoroalkyl substances (PFASs) in serum as part of the quality assurance programme under HBM4EU. Science of the Total Environment 847 157481. 2022.
DOIProficiency and Interlaboratory variability in the determination of phthalate and DINCH biomarkers in human urine: results from the HBM4EU project
Mol HGJ, Elbers I, Pälmke C, Bury D, Göen T, Esteban López M, Nübler S, Vaccher V, Antignac JP, Dvořáková D, Hajšlová D, Sakhi AK, Thomsen C, Vorkamp K, Castaño A, Koch HM. Proficiency and Interlaboratory variability in the determination of phthalate and DINCH biomarkers in human urine: results from the HBM4EU project. Toxics 10:57. 2022.
DOIEuropean interlaboratory comparison investigations (ICI) and external quality assurance schemes (EQUAS) for the analysis of bisphenol A, S and F in human urine: Results from the HBM4EU project
Vaccher V, Esteban López M, Castaño A, Mol H, Haji-Abbas-Zarrab K, Bury D, Koch HM, Dvorakova D, Hajslova J, Nübler S, Sakhi AK, Thomsen C, Vorkamp K, Göen T, Antignac JP. European interlaboratory comparison investigations (ICI) and external quality assurance schemes (EQUAS) for the analysis of bisphenol A, S and F in human urine: Results from the HBM4EU project. Environ Res 210. 2022.
DOIHBM4EU chromates study - Overall results and recommendations for the biomonitoring of occupational exposure to hexavalent chromium
Santonen T, Porras SP, Bocca B, Bousoumah R, Duca RC, Galea KS, Godderis L, Göen T, Hardy E, Iavicoli I, Janasik B, Jones K, Leese E, Leso V, Louro H, Majery N, Ndaw S, Pinhal H, Ruggieri F, Silva MJ, van Nieuwenhuyse A, Verdonck J, Viegas S, Wasowicz W, Sepai O, Scheepers PTJ, HBM4EU chromates study team. HBM4EU chromates study - Overall results and recommendations for the biomonitoring of occupational exposure to hexavalent chromium. Environ Res 201: 111984. 2022.
DOIHBM4EU Occupational Biomonitoring Study on e-Waste-Study Protocol
Scheepers PTJ, Duca RC, Galea KS, Godderis L, Hardy E, Knudsen LE, Leese E, LouroH, Mahiout S, Ndaw S, et al. HBM4EU Occupational Biomonitoring Study on e-Waste—Study Protocol. Int J Environ Res Public Health 18. 2021.
DOISelecting the best non-invasive matrix to measure mercury exposure in human biomonitoring surveys
Esteban López M, Arrebola JP, Juliá M, Pärt P, Soto E, Cañas A, Pedraza-Díaz S, González-Rubio J, Castaño A. Selecting the best non-invasive matrix to measure mercury exposure in human biomonitoring surveys. Environ Res. 204: 112394. 2021.
DOIMercury levels in feathers of penguins from the Antarctic peninsula area: geographical and inter-specific differences
Motas M, Jerez S, Esteban M, Valera F, Cuervo JJ, Barbosa A. Mercury levels in feathers of penguins from the Antarctic peninsula area: geographical and inter-specific differences. Int J Environ Res Public Health. 15: 9918. 2021.
DOIA Phased Approach for preparation and organization of human biomonitoring studies
Fiddicke U, Pack IK, Tolonene H, Sepai O, Esteban López M, Castaño A, Schoeters G, Kolossa-Gehring M. A Phased Approach for preparation and organization of human biomonitoring studies. Int J Hyg Environ Health. 232: 113684. 2021.
DOIContenidos con Investigacion .
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Dra. Beatriz Núñez Corcuera
Técnica Superior Especializada de OPI
Código ORCID: https://orcid.org/0000-0001-6551-9215
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Dra. Sonia Arca de Lafuente
Investigadora postdoctoral
Código ORCID: https://orcid.org/0000-0003-4750-0988
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Dra. Mónica Bartolomé Jimeno
Técnica Superior Especializada
Código ORCID: https://orcid.org/0000-0002-4031-1407
Listado de personal
Información adicional
Estudio de los determinantes de salud urbanos para la mejora del bienestar y la calidad de vida de la población.
Según Naciones Unidas, para el año 2050, el 70% de la población mundial vivirá en ciudades. En consecuencia, estas deben adaptarse a la rápida urbanización, el cambio climático, el aumento del consumo de energía y la creciente desigualdad social derivada de la falta de políticas urbanas eficaces. En los próximos años, el conjunto de actores políticos y sociales se enfrentarán al gran desafío de promover ciudades más saludables, sostenibles y resilientes. Para ello tendrán que proponer estrategias de prevención y promoción de la salud que mejoren el bienestar y la calidad de vida de su población de acuerdo con los Objetivos de Desarrollo Sostenible (ODS) y la Agenda 2030.
El objetivo principal del grupo es generar evidencias científicas que permitan desarrollar estrategias de Salud Pública orientadas a la mejora del bienestar y la calidad de vida de la población.
El grupo de investigación realiza diversas actividades de divulgación científica en colaboración con la Unidad de Cultura Científica del ISCIII, por ejemplo, la actividad “CIUDADES DEL FUTURO”.
COLABORACIONES
Departamento de Salud Ambiental. Madrid Salud. Ayuntamiento de Madrid.
EnvE Lab, Aristotle University of Thessaloniki (AUTH). Grecia.
Department of Environmental Social Science. Aarhus University. Dinamarca